Advanced Seminars in Behavioral Neuroendocrinology - Therapeutic Effects of Psychedelics
Summers
SN2ACKS: Systems and Neuroscience Networks Advanced Communication of Knowledge Seminars
Formerly: Advanced Seminars in Behavioral Neuroendocrinology

Therapeutic Effects of Psychedelics
Spring 2019
end
Date Speaker
streaming video
Title of the 1o Journal Paper Authors year,
journal
volume:
pages
food
Jan 11
UCL
173
Cliff Scheduling and Grading Information

SN2ACKS Seminar Success Guide

Intinerary, Schedule and Organization
CH Summers 2019
Jan 18
UCL
173
Cliff How to chose a paper, What makes a good talk, Guide to Seminar Design CH Summers 2019
Jan 25
UCL
173
Kevin
Krupp

Introduction to Psychedelics
Psychedelics as medicines: An emerging new paradigm
Background papers:
Vollenweider and Kometer 2010 Nature Reviews Neuroscience 11: 642-651 The neurobiology of psychedelic drugs: implications for the treatment of mood disorders

Flanagan and Nichols, 2018 International Review of Psychiatry DOI: 10.1080/09540261.2018.1481827 Psychedelics as anti-inflammatory agents

DE Nichols
MW Johnson
JCD Nichols

2017,
Clinical
Pharmacology
Therapeutics
101:
209–219
Tangi
Feb 22
UCL
173
Jaz
Yaeger
22-azidosalvinorin A exhibits antidepressant-like effect in mice
Background papers:
AV Williams, A Laman-Mahargb, CV Armstronga, S Ramos-Maciela, VA Minie, BC Trainor 2018 Progress in Neuropsychopharmacology & Biological Psychiatry 86: 166–174 Acute inhibition of kappa opioid receptors before stress blocks depression-like behaviors in California mice

C Nocjar, J Zhang, P Feng, J Panksepp 2012 Neuroscience 218: 138–153 The social defeat animal model of depression shows diminished levels of orexin in mesocortical regions of the dopamine system, and of dynorphin and orexin in the hypothalamus
JO Fajemiroye
PR Prabhakar
LC da Cunha
EA Costa
JK Zjawiony
2017
European
Journal of
Pharmacology
800:
96–106
Kevin
Mar 15
UCL
190
Jess
Hoynoski
Ketamine reduces aversion in rodent pain models by suppressing hyperactivity of the anterior cingulate cortex

Background papers:
Ossato et al., 2018 Neuropharmacology 141: 167 – 180 Neurological, sensorimotor and cardiorespiratory alterations induced by methoxetamine, ketamine and phencyclidine in mice

Lilius, Kangas, Niemi, Rauhala, Kalso, 2018 Brit J Anaesthesia 120: 818-826 Ketamine and norketamine attenuate oxycodone tolerance markedly less than that of morphine: from behaviour to drug availability

H Zhou
Q Zhang
E Martinez
J Dale
S Hu
E Zhang
KLiu
D Huang
G Yang
Z Chen
J Wang

2018
Nature
Communications
9: 3751:
1–13
DOI: 10.1038/s41467-018-06295-x
Jaz
Mar 22
UCL
173
Eric
Graack
3,4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for post-traumatic stress disorder in military veterans, firefighters, and police officers: a randomised, double-blind, dose-response, phase 2 clinical trial

Background papers:
Hake, Davis Wood, Tanner Loetz Sanchez, Ostrovskyy, Oleson, Grigsby, Doblin, Greenwood 2019 Physiology and Behavior 199: 343–350 3,4-methylenedioxymethamphetamine (MDMA) impairs the extinction and reconsolidation of fear memory in rats

Fortress, Smith, Pang 2018 Neuropharmacology 137: 372-381 Ketamine facilitates extinction of avoidance behavior and enhances synaptic plasticity in a rat model of anxiety vulnerability: Implications for the pathophysiology and treatment of anxiety disorders
MC Mithoefer
AT Mithoefer
AA Feduccia
L Jeromet
M Wagner
J Wymer
J Holland
S Hamilton
Berra Yazar-Klosnski
A Emerson
R Doblin
2018
Lancet
Psychiatry
5:
486-497
Jess
Apr 26
UCL
173
Kevin
Krupp
Psychedelics promote structural and functional neural plasticity



Background papers:
LP Cameron, CJ Benson, BC DeFelice, O Fiehn, DE Olson 2019 ACS Chemical Neuroscience DOI: 10.1021/acschemneuro.8b00692 Chronic, intermittent microdoses of the psychedelic N,N-Dimethyltryptamine (DMT) produce positive effects on mood and anxiety in rodents



M Fuchikami, A Thomas, R Liu, ES Wohleb, BB Land, RJ DiLeone, GK Aghajanian, RS Duman 2015 PNAS 112: 8106–8111 Optogenetic stimulation of infralimbic PFC reproduces ketamine’s rapid and sustained antidepressant actions
C Ly
AC Greb
LP Cameron
JM Wong
EV Barragan
PC Wilson
KF Burbach
SS Zarandi
A Sood
MR Paddy
WC Duim
MY Dennis
AK McAllister
KM Ori-McKenney
JA Gray
DE Olson
2018
Cell
Reports
23:
143–153
Eric
Therapeutic Effects of Psychedelics
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